Go big
I use cohort studies and large datasets to find, across whole populations, who ages well and who doesn’t.
The Dunedin Study
1,037 people born in Dunedin, New Zealand, in 1972–73 and assessed from birth to age 45, including brain MRI at 45. Following one cohort for decades shows who ages fast, who ages slow, and what came before.
Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohortMolecular Psychiatry, 2021