How can we help more people maintain cognitive functioning as they age?

Maxwell ElliottAssistant Professor of Psychology, University of Minnesota

Some older adults develop dementia and disability around retirement. Others keep exceptional cognitive function into their 90s. I study these individual differences in cognitive and brain aging.

I’m recruiting PhD students and a postdoc

UK Biobank

About half a million UK adults, aged 40 to 69 when they joined in 2006–2010, with brain imaging for a large subset. It lets measures built in one cohort be tested in very large samples.

ADNI

The Alzheimer’s Disease Neuroimaging Initiative has followed older adults with and without cognitive impairment since 2004, with repeated brain scans.

Go small

In tandem, I study smaller, informative groups in depth, to improve how we measure aging and to test targeted hypotheses.

One person at a time

Measurement error in a single standard scan can hide real change in one person’s brain.

Find the windows

Prevention, earlier

Throughout my work, I look for critical windows in the lifespan for prevention and treatment. Much of it looks at midlife, decades before dementia usually appears.

All papers

Lexis diagram of the studies behind this research Age from 0 to 100 plotted against calendar years 1970 to 2030, so each life runs as a diagonal line. The Dunedin Study cohort, born in 1972 and 1973, is a narrow band rising from birth to age 45. UK Biobank covers people aged 40 to 69 when they joined in 2006 to 2010, rising with time. ADNI covers older adults from 2004 onward. born 1930 born 1950 born 1990 born 2010 1970 1980 1990 2000 2010 2020 2030 0 20 40 60 80 100 age calendar year midlife, 40 to 65 UK Biobank ADNI brain MRI at 45 Dunedin Study now
Age against calendar year: every life runs as a diagonal. Bands show the ages each study covers, approximately. The zoomed view is an illustration, not real data.

Selected papers

All 41 papers
  1. 2026

    Precision estimates of longitudinal brain aging capture unexpected individual differences in one year

    Nature Communications

  2. 2025

    DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease

    Nature Aging

  3. 2025

    Within-individual precision mapping of brain networks exclusively using task data

    Neuron

  4. 2024

    Precision brain morphometry using cluster scanning

    Imaging Neuroscience

  5. 2021

    Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort

    Molecular Psychiatry

  6. 2020

    What is the test-retest reliability of common task-functional MRI measures? New empirical evidence and a meta-analysis

    Psychological Science

Join the lab

I’m recruiting at the University of Minnesota. If my work interests you, please don’t hesitate to reach out.

PhD students, 1–2

Open

Through the Clinical Science and Psychopathology Research program (my primary appointment) or Personality, Individual Differences, and Behavior Genetics.

Postdoctoral fellow

Open

Email me and we can discuss further.

Maxwell Elliott
Maxwell ElliottDepartment of Psychology, University of Minnesota, Minneapolis